•       Critically evaluate current and novel therapies used to manage and treatment of respiratory disease and its associated complications.

•       Critically evaluate relevant literature (peer – reviewed publications) relating to the therapeutic management of respiratory problems.

•       Engage with the multidisciplinary team in the approach to managing complex respiratory problems.

Work submitted after the deadline will be recorded as late, unless an extension or deferral has been obtained before the deadline. The penalty for late work is 5 marks for work submitted up to 24 hours after a deadline, and 5 marks per day after this, including weekends

To apply for extension deferral, mitigating circumstance or late penalty wavier please follow the following link https://portal1.chester.ac.uk/registryservices/Pages/student-mitigatingcircumstances.aspx

The systematic review could be structuring as follow, remember it is a recommendation

Title it needs to be narrow and formulated based on PICO.

Abstract (200-300 words) should be structured as follows:

·       Back ground: One or two sentences about the intervention

·       Aim: Main aim using PICO

·       Method: Databases used for search, study design and outcomes you are interested in.

·       Results: Total number of studies with total number of patients, as well as the results of the outcomes reviewed

·       Conclusion: Main conclusion from the Systematic Review.

Key words: 4- 5 keywords.

The introduction (~200-300 words)

·       Should have a brief back ground about the therapeutic intervention and how it works and present a rationale for selection of this therapeutic intervention.

·       What are the gaps in the previously done SR, and why yours will be different.

·       The introduction should end by the aim of the systematic review (i.e. clear PICO question with clear outcomes).

The method (~500-600 words) should include:

·       Search strategy: An appropriate search strategy with at least two databases used. Relevant Keywords and their synonyms.   You need to copy each search strategy from each database. any filters used. Date of search.

·       Inclusion and exclusion criteria. What study design you are looking for is very important. Patients characteristics, what type of treatment they are receiving.

·       N: B. Any language or date restriction needs to be mentioned. i.e. Include the time frame for the search. Also, any language restrictions added, for example studies in English. Also, any language restrictions added, for example studies in English.

·       Outcomes: What are the outcomes that you will look at, how are they defined and how will they be measured?

·       Reviewing process: What is the screening, eligibility and inclusion process that took place.   Have you included open access sources only, or have you tried to contact authors to get access to non-free articles?

·       Data extraction: What data you will extract from each study? e.g. study names, dates, Patient’s characteristics, participants’ numbers, dose, interventions, outcomes, limitations, country where the study was conducted, etc.

·       Assessment of Risk of Bias: You should describe the tool that will be used to assess the risk of bias. For example, if you are looking for RCTs, you will use JADAD score or Consort check list to assess the risk of bias. Cohort and observational studies New Castel Ottawa.

The results (~400-500 words)

·       You must provide a Prisma flow chart as a figure

·       Describe the stages of the Prisma flow charts while referring to the figure of the Prisma flow chart

·       Produce a table of results which compares the findings of each outcome in columns not rows (see examples). Remember the number of the included studies should be the same as by the end of the Prisma flow chart

·       Subheadings are needed for each outcome and you should describe the key results for each outcome under these headings. Do not evaluate the results at this stage and try to avoid describing each study one by one.

·       e.g. an outcome might be ‘mortality’

·       You would write about the mortality findings from all of the studies, but without writing these 1 by 1 as the table highlights this more clearly. For example, 4 studies examining 2000 patients find an increase in the mortality rate after this intervention while 2 studies have no effect on mortality. i

·       The results of the risk of bias of each study. If it is JADAD score or Newcastle Ottawa this is best presented by inclusion in the table. If it is another tool, then this could be written under a subheading.

The Discussion (~700 words)

·       You should discuss the data presented in the results in the table of data extraction

·       You need to evaluate the evidence and critically analyse the effect of the selected treatment on each outcome.   Look closely at each study method and results to evaluate the evidence.

·       Compare your systematic review with other published systematic reviews and other relevant literature.

·       What could be the mechanism (molecular mechanism) of the efficacy and the safety of the selected intervention

·       Consider the limitations of your systematic review. General and subject specific limitation.

The Conclusion (~100 words)

·       Concise conclusion is required to answer the key question about if this intervention is safe of efficient in treating the selected condition or not, your answer should be based on what you have discussed in the discussion and based on the evidence coming from the reviewed studies. It is recommended to propose a future research idea is recommended

Reference list

·       In Vancouver

It is important to:

·    Ensure that all the figures and tables are self-explanatory.

·    Avoid using wordy tables, tables should be clear and easily to be read using the relevant abbreviations

·    Present two tables one table for study characteristics and another table for the outcomes

·    All tables should have a number and titles above the table, but the abbreviation list should be below the tables.

·    Figures should have titles and numbers below the figures, as well as the list of abbreviation.

·    Don’t forget to refer to the table and the figures int the text.

What you need to include in the draft?

Submit a word document with your Prisma flow chart, the table of data extraction and 500 words from the discussion section on