Describe the process by which cells respond to the presence of an A–G pairing of two bases in a newly replicated section of DNA in order to restore the correct base sequence.

Question 1 (10 marks)

This question is associated with Sections 1.5–1.7. It assesses the module learning outcome KU1.

• Describe the role of each of the following enzymes in genomic DNA replication:
  • DNA primase
  • DNA polymerase
  • DNA topoisomerase
  • DNA helicase.

(4 marks)

• Describe the process by which cells respond to the presence of an A–G pairing of two bases in a newly replicated section of DNA in order to restore the correct base sequence.

(4 marks)

• How does the synthesis of the two new strands during DNA replication differ?

(2 marks)

Question 2 (10 marks)

This question is associated with Sections 3.6 and 3.8 and with Activity 3.5. It assesses the module learning outcomes KU1 and KS1.

qPCR and sequence analysis are often used in combination to assess CYP2D6 gene status by determining copy number and DNA variants. An analysis of two parents with the DNA variants present on each of the individual’s chromosomes is shown below:

• Father: *10, *1–*1
• Mother: *4, *10
• Determine all possible CYP2D6genotypes of their children using a Punnett square.

(4 marks)

• Using information from Table 1 (reproduced from Topic 5 Table 3.3), what are the predicted CYP2D6 enzyme activity scores based on the predicted genotypes for each of their possible children?

(2 marks)

• Based on the consensus predicted activity scores presented in Table 2, what proportion of their children could potentially be predicted to have an intermediate metaboliser status for nortriptyline, based upon the likely impact of these sequence variants on CYP2D6 enzyme activity? Explain your answer.

(2 marks)

• Which parent is likely to experience greater pain relief from codeine? Explain your answer.

(2 marks)

Question 3 (30 marks)

This question is associated with Sections 3.3, 3.8, 4.5, and 4.7. It assesses the module learning outcomes KU2, CS1, CS2 and KS2.

Michael, a young adult male, is referred from a specialist cardiac clinic for genetic testing to investigate a possible genetic origin for hypertrophic cardiomyopathy. He receives initial counselling about the genetic testing process, a family history is collected, and a blood sample is taken for further genetic investigation. Michael’s mother has no sign or symptoms of the disease and neither do his two younger sisters, who are identical twins. His father is deceased and he is uncertain as to what the cause of his father’s death was. It is explained to him that the investigation of his DNA uses targeted genome sequence analysis of the exons of genes that are known to be associated with hypertrophic cardiomyopathy, and after counselling he consents to his DNA being tested.

• In Topic 5 Activity 3.2 you practised collecting UV absorbance data from a DNA sample. Using the DNA and RNA quantitation laboratory, perform an analysis of the genomic DNA that has been isolated from Michael’s blood sample, which is labelled as DNA3.
  • Present your absorbance findings using a table similar to Table 26 in Practical Workbook 2. Comment on the values obtained from the two experimental control samples.

(6 marks)

• Provide an analysis of your absorbance values collected from the undiluted DNA3 sample to confirm that the sample is free of contamination from co-purified protein and therefore suitable for further analysis.

(2 marks)

• A sample of Michael’s DNA is to be sent to a DNA sequencing laboratory for exon sequence analysis. Determine the concentration of the undiluted DNA3 sample using data from the 1 in 2 and 1 in 5 diluted samples. What volume (in μl) of the undiluted DNA would you collect to provide a sample containing 5 μg of DNA? Show how you determined both of these values.

(6 marks)

• (14 marks in total)
• After exon sequence analysis has been performed on DNA3, the findings indicate that Michael carries a mutation in one of his two copies of a gene called MYH7. Mutations in MYH7, which encodes a protein called myosin heavy chain 7, are a known cause of hypertrophic cardiomyopathy and they exhibit a dominant pattern of inheritance. It is likely that Michael’s father also carried the same mutation in MYH7that Michael carries.
  • Using the Human gene expression database, research which tissues express the MYH7gene. Provide an image of your findings and the number of MYH7 transcripts present in tissues expressing the gene. What other tissue might be affected by a mutation in the MYH7 gene?

(5 marks)

• One of Michael’s younger sisters, Hannah, is to attend a genetic counselling clinic as she is planning to have children. Since Michael’s investigations, an additional molecular analysis has been performed that confirms that their mother does not carry any mutation in any gene likely to cause hypertrophic cardiomyopathy.

Before Hannah undergoes molecular testing herself, she is to receive counselling to learn more about the genetics of the disorder.

Based upon the information you have, draw a tree for the family using relevant symbols and identify Michael and Hannah on the pedigree.

(5 marks)

• What can you tell Hannah about her likely genotype and whether she may herself be affected by hypertrophic cardiomyopathy?

(3 marks)

• What issues arise from the genetic testing of Hannah with regard to her sister?

(3 marks)

• (16 marks in total)

Question 4 (50 marks)

This question is associated with Sections 2.6 and 2.7. It assesses the module learning outcomes CS2, KS2, KS5 and PPS1.

You are tasked with screening a group of individuals to determine their metaboliser status for nortriptyline ahead of a clinical trial in which ultra-rapid metabolisers for nortriptyline are to be excluded. In Activity 2.2  you collected data from the Drug metabolism laboratory and drew a standard curve for nortriptyline.

You should now prepare a standard curve for the metabolite using the following concentrations of 10-hydroxynortriptyline: 5, 10, 20, 40, 60, 70 and 80 nmol l^–1.

Collect data from the five individuals in Group 4, use the two standard curves to estimate the concentration of drug and metabolite in each serum sample, and calculate the metabolite ratio for each individual in Group 4 using the guidance provided in Topic 5 Box 2.5. Space to record your data and suitable graph paper is provided in Practical Workbook 2, pages 61–65.

From your study, you should then prepare a written report outlining the study and your findings which answers parts (a)–(d) below. These parts will guide you to the content and style required in this report. A suggested length for each section is provided to help your planning and writing. Note that the total word count for all parts combined is a maximum of 700 words.

You practised writing a short report for TMA 04 using the same section headings, and you may find it helpful to review any feedback your tutor provided as to the style and content of each section.

• Introduction. This should be a brief explanation, written in your own words, of the background to the assays you performed, including:
  • the objectives of your study
  • the reason why metabolism varies between individuals
  • a brief outline of approach you have used
  • criteria for assigning metaboliser status.

(6 marks, around 150 words)

• Method. This should be a summary of the experimental aspects of how you collected and processed your data. You should write using the past tense and the text should allow another individual to repeat your study by following the guidance in Practical Workbook 2and obtain similar results. You should include only information on the following:
  • how you collected peak area data and how many repetitions you performed
  • how you prepared your 10-hydroxynortriptyline standard curve
  • how you used your standard curves to determine the concentrations of drug and metabolite in serum samples
  • how you calculated the metabolite ratios for nortriptyline.

(8 marks, around 150 words)

• Results. You should present a written description that guides the reader sequentially through your data that is summarised in a series of tables and figures, as detailed below. You should note any data points you discarded due to detector saturation. This written description should be around 300 words.

Your tables and figures should be inserted into your report, and you should refer to each within the written description of the data. Each figure and table should have a title. The following data should be presented:

• Figure 1: your standard curve for 10-hydroxynortriptyline.
• Figure 2: an image of the HPLC trace for individual 4-001, with the markers positioned for collection of the nortriptyline peak area.
• Table 1: your calculated drug and metabolite concentrations for the Group 4 individuals, their metabolite ratio, and metaboliser status – using the format given below in Table 3.

Note: the titles of your figures and the contents of your Table 1 do not count toward the word count total for Question 4.

(30 marks, around 300 words)

• Interpretation. This should be a written description that summarises the interpretation of the data that you have presented as the metabolite ratios and metaboliser status of the Group 4 individuals in your Table 1. Indicate any individual/s that you recommend be excluded from the planned clinical trial because of their metaboliser status.

(6 marks, around 100 words)

Your total word count for parts (a), (b), (c) (excluding table contents and figure titles) and (d) combined should not exceed 700 words.

Develop a personal mission statement that explains the type of leadership you desire to practice.

Description

Checklist:

Introduction section:

Develop a personal mission statement that explains the type of leadership you desire to practice. For an example, see the Leadership Skill-Building Exercise 1-3 – My Leadership Portfolio, in Chapter 1 of the text (DuBrin, 2019). Conduct research to identify two leaders in your industry that appear to be closely aligned with your personal mission statement. Provide details on what makes each leader successful in their industry. Using the Leadership Self-Assessments (Quiz 1-1 and Quiz 1-2) and the Leadership Skill-Building Exercise 1-1 found in Chapter 1 of the text (DuBrin, 2019), analyze your current state of leadership readiness and identify one-to-two opportunities for development. Provide recommendations for your personal leadership development based on your research and analysis. Provide a conclusion that should summarize the primary points of the paper and provide a call to action. Ensure substantive integration of appropriate current, and reliable resources, including in-text citations throughout, with a corresponding item on the reference list. A minimum of two viable sources are required [no older than 3 years]. Your response should be spell and grammar-checked and demonstrate correct mechanics and appropriate writing style. Format your paper using APA 7th edition, including section headings.

prepare an 8-10 page position paper, based on appropriate nursing research and evidence that discusses your position on “Stress Management of Nurses”

Description

Current Issues paper related to “Stress Management of Nurses” Finding and reading a variety of Nursing or allied health journal peer-reviewed articles, online, and textbook resources about the nursing issue topic, and ultimately choosing a total of six minimally to use for the Paper. Sources must be current (within the past 5 years). All of the resources must be from a nursing or allied health peer-reviewed journal. Issues and Trends Position Paper Structure Please prepare an 8-10 page position paper, based on appropriate nursing research and evidence that discusses your position on one of the following topics: Proper grammar (no slang), sentence structure, paragraphs, punctuation, and spelling. Paper Outline ( 8-10 pages) Title Page (cover) Abstract (separate page with header) Introduction Issue Presentation ( include your professional opinions as well as research) Evaluation Reference’s – with correct alignment and placement (separate page at the end of the paper). I have attached the six references I found for the information needed in the paper. Please incorporate these specific references I have listed below. Reference 1- https://onlinenursing.duq.edu/blog/managing‑nurse‑stress/ Reference 2- https://link.springer.com/article/10.1007/s12646‑018‑0454‑x Reference 3- https://onlinelibrary.wiley.com/doi/full/10.1111/jocn.15553 Reference 4- https://assets.researchsquare.com/files/rs‑970198/v1/2dcaf313‑ce1f‑4bd0‑9ff5‑86390ff92f6a.pdf? c=1635283110 Reference 5- https://www.registerednursing.org/articles/how‑manage‑stress‑nurse/ Reference 6- https://online.ahu.edu/blog/managing‑nurse‑stress/

What can You do as a LPN to always make sure your patients are safe?

Description

Patient Safety Paper

This assignment is a 2 page paper on the importance of Patient Safety. What can You do as a LPN to always make sure your patients are safe?

Identify what appears to be the most appropriate solution/s to the problems identified & give reasons for your choice.   Explain why other solutions have been rejected.

THE BRASS RAIL

Alice Masters is an Area Manager employed by a restaurant chain with branches across the UK. Six weeks ago she moved Brian Marsden to make him manager of one of the restaurants situated in Wanden. There has been a period of management instability at this branch. Prior to Brian two ineffective managers had been employed who each worked at this branch for about six months. Then followed a branch manager who was competent but who had to return to his home country at short notice because of urgent family problems. He had also only been in the job for six months. Alice knows that Brian is technically competent and he has managed a number of different branches in the seven years he has been with the group. However, Alice is also aware that employees have sometimes found him rather strict. On one occasion a branch he managed had to be closed for a week because of staff shortages due to a combination of staff leaving and others refusing to work with him.

There is one Deputy Manager, Diana Miller, at the branch. Diana and Brian arrange for one of them at least to always be present when the restaurant is open. Diana concentrates on the paper work but if there are any queries she simply refers them to Brian if at all possible. Each shift also has a shift supervisor, who is simultaneously a member of the waiting staff. The shift supervisors have smaller sections to deal with than other waiters but are reluctant to help out when members of waiting staff on other larger sections are over-worked.

Since Brian took over the Wanden branch Alice has noticed that sales have begun to recover though she has also noticed that labour turnover has increased significantly. Few members of staff have been there for as long as a year. Alice is aware that the previous branch manager had not had time to deal with a number of the managerial problems that had accumulated at the branch. She is also aware of some of the innovations that Brian has introduced at the branch. These innovations have included a ‘side orders competition’ for waiting staff. ‘Side orders’ consist of items such as bread and olives. The winner of this three-week competition for the highest sales of side orders gets a £50 gift voucher. All eight members of waiting staff are eligible to compete.   Alice is also aware that Brian has reactivated the distribution of training manuals for the waiters. Training manuals are also used for kitchen staff and their use had been allowed to lapse. A further change has been the more adequate laying of tables to include cutlery for side orders, wines glasses and side plates.

One day Alice is surprised to receive a formal grievance from a waitress employed at the Wanden Branch. Alice’s surprise is particularly because the grievance procedure is so infrequently used. The waitress’s complaint is primarily about her demotion from ‘waiter’ to ‘runner’. Alice arranges to see the waitress, Tracey Walters, and has a long discussion with her. The main issues that arose as a result of the interview are:

1. Tracey has been demoted because of a ‘three mistakes’ rule instituted by Brian. This rule involves demoting waiters to runners if the waiter makes three mistakes in one shift. Tracey has been the first person to suffer under this rule and although her basic rate of pay has not been affected, her capacity to earn tips has been significantly reduced. The mistakes Tracey admits she made were:

• Not to put ice in the glass of water when a customer had ordered iced water.

• Activating the ‘No’ button on the credit card machine, instead of getting the customer to activate the button themselves indicating that they did not want to include a tip. Tracey explained to Alice that she had done this herself so as not to irritate a customer who had already left a generous cash tip.

• Leaving a customer unattended to help a colleague on another section. Tracey explained that she had done this because the customer had only just come in and her colleague had had some customers waiting for 15 minutes because of a surge of customers into his section.

Tracey further maintains that, when Brian had informed her of her demotion, Brian had accepted that had she a good record but had insisted that rules were rules and that he did not want to hear any ‘buts’. Brian had added that the demotion would enable Tracey to learn how to work properly whilst doing ‘running’ work. It would also encourage other waiting staff to smarten up their act for fear that the same action would be taken with them. Tracey maintained though that her mistakes had been done during a second 12-hour shift. She has worked a 12 hour shift the previous day and she had agreed to work this second long shift because of staff shortages. Tracey also maintained that there had been no opportunity for to argue her case for not being demoted before the decision was taken by Brian.

2. Tracey is the second longest serving waiter and has been at the branch for more than two years. She combines her work with a Part-Time Business Studies degree course she is pursuing.

3. The work of ‘runners’ particularly involves fetching food from the kitchen, collecting dirty plates, laying tables, bringing drinks from the bar and returning empty glasses to the bar. They get 5% of the tips of waiters, whilst the bar staff and kitchen staff get 10%.

4. Sales are monitored by Brian but Tracey maintains that this has encouraged some staff to concentrate on sales credited to them and ignoring other work, such as helping over-worked staff and fetching food from the kitchen when a runner is not available. Such activity is also likely to increase their tips but not overall sales.

5. Whilst Training Manuals have been distributed there is little guidance on how to use them effectively. This is unfortunate because many of the questions in the manual are about situations that are not explained in the manual. It is even more unfortunate because the members of waiting staff are judged on the basis that they know everything that is in the manual.

6. The standards of management and supervision vary considerably. When Brian is not on shift there is a more relaxed atmosphere, which is however not always more productive. Tracey maintains that when Brian is in the restaurant some of the staff make great efforts to look busy, which can be in considerable contrast to their behaviour when Brian is either not on shift, or is working in the office.

Write a report of 2,000 in answer to the following questions:

Q1.Identify the problems in the case from the perspective of the Company that is running this restaurant. In identifying the problems, differentiate between the symptoms of any problems and the causes.   (50% marks)

Q2. Identify what appears to be the most appropriate solution/s to the problems identified & give reasons for your choice.   Explain why other solutions have been rejected.   (50% marks)

Make reference to the models and theories referred to on the module in answering these questions.

END

Which one, (apple or LG), is better and more recommended to be used in health care for the nowadays and in the future?

Name of the paper:

Survey on Digital and Electronic Technologies’ Impacts on the Healthcare System: LG vs. Apple

A. When each section is completely written, please send it to us so that we read and review it with our instructor.

1. Number of up-to-date sources, to be used with the paper, should exceed 100 sources. We need to get a full copy of all the sources you are going to use. So, please send us a copy of all the sources.

The following are the Writing Instructions to the writer and what this paper should contain, and what topics to be included (We look forward that the writer is creative in including other relevant important topics he may find or suggest also):

1. The whole paper should focus on computerized and digitalized technology and its role in delivering services in health sector. The focus should NOT be on health, but rather, the role of Apple and LG applications in health service. A very vivid comparison should be demonstrated between these two throughout the whole paper.

1. All so far new inventions made in this field by Apple and LG

• When did either of Apple and LG start with these digitalized services? The step-by-step progress of each one should be elaborated.

1. Applications in use by both of them in this field. How those applications developed throughout years.
2. How far is it easy or complicated to use these Apple-and-LG applications by doctors, other health personals and patients?
3. The difference between Apple and LG applications

• Different ideas in different sections of the paper should be elaborated through using figures or tables, etc.
• Security & privacy: Are recording data kept confidentially?

1. TeleHealthcare in each of Apple and LG
2. Electronic medical record in each of Apple and LG
3. RFID in each of Apple and LG should be included

• Showing, mentioning and explaining some practical examples for each of those apps of Apple and LG, and how they function
• Which one, (apple or LG), is better and more recommended to be used in health care for the nowadays and in the future?

• Integrated medical records Electronic medical records allow all patient histories, test results, diagnoses and relevant information to be stored centrally in an online location.

1. Increased mobility Mobile software applications (aka mobile apps) are key to improving accessibility for patients and healthcare professionals.

• Digital transformation in healthcareis the positive impact of technology in healthcare. Telemedicine, artificial intelligence (AI)-enabled medical devices, and blockchain electronic health records are just a few concrete examples of digital transformation in healthcare
• Wonders of artificial intelligence Artificial intelligence (AI) is more than just a digital transformation trend in healthcare. AI represents the epitome of medical innovation and industry players are eager to invest millions in it.

• Treating patients with virtual reality Virtual Reality (VR) is the pièce de résistance of digital transformation in healthcare. Its myriad of applications are profoundly changing the way patients are being treated.

• Patient electronic portals A patient portal is a secure online application that provides patients access to their personal health information and 2-way electronic communication with their care provider using a computer or a mobile device.Studies have shown that patient portals improve outcomes of preventive care and disease awareness and self-management.

1. Telemedicine Telemedicine is defined as the use of telecommunication technologies to facilitate patient to provider or provider to provider communication. Communication maybe synchronous with real-time 2-way video communication or asynchronous transmission of patient clinical information. In addition to communication, telemedicine may provide health information that is collected remotely from medical devices or personal mobile devices. This information may be used to monitor patients, track or change their behaviour

• Remote patient monitoring Studies evaluating community based Remote patient monitoring (telemonitoring) have shown that it improves patient outcomes for certain chronic conditions including; heart failure, stroke, COPD, asthma and hypertension. Patient data management systems (PDMS) are systems that automatically retrieve data from bedside medical equipment (namely patient monitor, ventilator, intravenous pump, and so forth).

• Electronic incident reporting Electronic incident reporting systems are web-based systems that allow healthcare providers who are involved in safety events to voluntarily report such incidents. Such systems can be integrated with the electronic health record (EHR) to enable abstraction of data and automated detection of adverse events through trigger tools.

• Improved Access to Medical Information and Data: One of the biggest benefits of the digital revolution has been the ability to store and access data. Healthcare professionals can now retrieve patient data from anywhere. Also, the intranet and internet have allowed healthcare professionals to share medical information rapidly with each other, resulting in more efficient patient care.

• Big Data and Cloud in healthcare Another great benefit of digital technology is that it allows clinicians to gather big data in minimal time. For those conducting epidemiological studies, research, or clinical trials, digital technology allows for the instant collection of data from a much more diverse and larger population than ever before. The generation and collection of huge amounts of data from a number of different sources in the healthcare field are now possible. This data is then used for analytics, making predictions about possible epidemics and ultimately preventing deaths.

• Health Apps: The digital revolution has also resulted in the development of hundreds of health apps. These apps enable patients to monitor their health and disease, provide them medical information, allow them access to test results and prompt them when it is time to get their check-up. Also, healthcare apps enable healthcare workers to quickly check on test results, drug dosing recommendations and other information they need urgently.

• Mobile health (applications used in detecting or preventing health issues) Mobile health (i.e. mHealth) is the use of mobile devices such as smartphones and tablets, to deliver healthcare and preventive health services. With wearable devices such as Fitbit or Apple Watch, people are able to monitor their heart rate and be informed of anything out of the ordinary. Healthcare providers also utilise mobile technology to access patients’ records and to communicate with patients and among providers.

• Telehealth and telemedicine (remote access and use of healthcare services) Telehealth is the use of information and communications technology (ICT) to access healthcare services remotely. Access to healthcare, especially for people who live in rural areas or have limited mobility, would improve with telehealth and telemedicine. For instance, people can use their mobile phones or other devices to log food that they ate , medication, and blood sugar levels that can be reviewed by nurses remotely.

• Consumer tech used to monitor and manage health data (wearables) The consumer’s use of wearable technology to monitor their own health has become mainstream over the last few years. Fitbitnot only counts the number of steps taken per day, monitors heart rate and sleep, but also predicts approaching menstrual cycles and fertile windows for women. A wearable device might even save a life in an emergency.
• The growth of wearable medical devices wearable medical device marketis expected to reach more than $27 million by 2023, a spectacular jump from almost $8 million in 2017. Some of the most common of these devices include:

1. Heart rate sensors
2. Exercise trackers
3. Sweat meters – used for diabetics to monitor blood sugar levels.
4. Oximeters – monitors the amount of oxygen carried in the blood, and is often used by patients with respiratory illnesses such as COPD or asthma.

• Importance of Online Health Education/Awareness Another key benefit of digital technologies is the availability of online education, specifically in regard to healthcare, health awareness. Today, there is a plethora of information available on the internet, yet you are not sure about its veracity or authentication

• Health Apps keep healthcare on your fingertips The digital revolution has also resulted in the development of health apps. They enable health monitoring; provide medical information, access to healthcare service providers and much more.

• Wearable Telemedicine Technology for the Healthcare Industry

• LG Electronics partnership with Amwell in developing new digital health solutions. What has this to say to Apple‘s digital health solutions?

• Benefits of digital health and Digital health can make healthcare more accurate Digital health has the potential to prevent disease and lower healthcare costs, while helping patients monitor and manage chronic conditions. It can also tailor medicine for individual patients. Electronic health records are one way to reduce medical errors, particularly by reducing mistakes made in administering medication.

• Digital Health Technologies Lead to More Empowered Patients Managing chronic illness is leading practitioners away from traditional paternalistic healthcare systems, in which healthcare providers make decisions with little to no input from patients, toward patient-centered models, in which patients are empowered to manage their own care.

• Digitalization can help make health systems responsive and sustainable Digital health technologies can improve access to health services, reduce costs, improve quality of care and enhance the efficiency of health systems. They can also provide opportunities for self-care. For example, remote monitoring devices and wearables help people better manage their own health, thereby reducing the burden on health systems and helping to make them more sustainable. Technologies that help people live healthier lives can also reduce costs for health systems.

• Digital health enables the transition from treatment to prevention Digital health technologies offer ways to self-manage health, with a focus on preventing disease and illness rather than simply treating them. Digital devices are already helping to track heart rate and blood sugar.

• Digital health systems call for modified roles of health-care professionals Digital health technologies can enable patients to receive care without physically going to a hospital or clinic. This means that health-care professionals will need to have the skills to use digital health tools, and to guide patients in understanding and using digital solutions to improve their health.

• Digital health systems can help reduce inequalities in health Telemedicine already offers remote medical services using information and communication technologies. It can serve people in isolated areas by providing access to medical services that may not otherwise be available or affordable.

1. Digitization of Health Records Storing, management, and transmission of data becomes easy and quick. Support for clinical decisions is made available to professionals and patients; making it possible to take better, more informed medical decisions.

• Improved Patient Care Technology has placed at the disposal of the healthcare community various potent tools to improve patient care. Since Electronic Health Records (EHRs) are easily available to physicians, they can access complete medical histories of patients and make the most well-considered medical decisions. Doctors can quickly identify possible medication errors.

Submit a 4 page reaction paper on chapter 5 in the book How Soccer Explains the World: An Unlikely Theory of Globalization by Franklin Foer.

Description

Submit a 4 page reaction paper. In the first two pages, give a reaction on chapter 5 in the book How Soccer Explains the World: An Unlikely Theory of Globalization by Franklin Foer. In the 1st two pages, provide a paragraph or two outlining an instance of cheating in sports. For pages 3 and 4, provide a reaction to the readings on cheating in sports. Bring in Foer as well if you choose

create thesis statement – issue of Indigenous contributions to Canada.

Description

create thesis statement – issue of Indigenous contributions to Canada. Your general framework should be that of refuting common stereotypes of Indigenous peoples as takers instead of contributors to the country we live in. You should focus on two areas of historical contributions as well as the basis for ongoing contributions in the future. essay outline included with sources needed –

1. Introduction
2. Indigenous people have always faced discrimination and racism due to historical events. Mainstream images have impacted the way society accepts Indigenous people.
3. Indigenous people have played a historical role in the shaping of Canada. Their early contributions to aiding European settlers to adapt to Canadian’s climate, and today play an important role in the support of climate change, but there are still the underline issues of racism, and discrimination that stereotype Indigenous people as takers instead of contributors.

1. First body paragraph – Historical Contributions

1. Indigenous people provided European settlers with live skills to survive in Canada’s climate.
2. Indigenous people were able to help settlers adjust to the new land and shared their knowledge and expertise.

• Indigenous people taught settlers how to build transportation and housing. Including canoes, small boats and cedar homes.

1. They were able to provide and teach settlers to use natural medicines to help the ill.

III. Second Paragraph – Military

1. Indigenous people have a huge contribution during the first and second world wars.
2. Indigenous people enlist in the armed forces to support their country.

• Indigenous people had to overcome unique cultural challenges.

1. Women join the front lines as nurses and provide medical support during the wars.

1. Third Paragraph – Future Environment and Climate
2. Indigenous peoples’ contribution is essential in designing and implementing solutions for ecosystem.
3. Traditional knowledge and heritage can contribute to environmental assessment and sustainable ecosystem management.

1. Conclusion
2. Indigenous people have played a historical role in the shaping of Canada. Their early contributions to aiding European settlers to adapt to Canadian’s climate, and today play an important role in the support of climate change, but there are still the underline issues of racism, and discrimination that stereotype Indigenous people as takers instead of contributors.
3. As stated, Indigenous people have had immense contributions to Canada’s society and culture. We must continue to educate non-Indigenous people about the detrimental affects systemic racism and systemic barriers have on Indigenous people.

Bamforth, Douglas B. “Indigenous people, indigenous violence: Precontact warfare on

     the North American Great Plains.” Man (1994): 95-115.

Cameron, Laura, Dave Courchene, Sabina Ijaz, and Ian Mauro. “‘A Change of Heart’:    

       Indigenous Perspectives from the Onjisay Aki Summit on Climate Change.” Climatic

Change 164, no. 3-4 (2021): 43.

Hendley, Matthew C. “Timothy C. Winegard. Indigenous Peoples of the British

     Dominions and the First World War.” The American Historical Review 118, no. 2

(2013): 486-87.

NoiseCat, Julian.“Slaying the Carbon-Consuming Colonial Hydra: Indigenous
Contributions to Climate Action.” Development 59, nos. 3-4 (2016): 199-204.

Thomson, Duane. “The response of Okanagan Indians to European settlement.” BC  

     Studies: The British Columbian Quarterly 101 (1994): 96-117.

Werhun, Cherie D, and April J Penner. “The Effects of Stereotyping and Implicit Theory  

     on Benevolent Prejudice Toward Aboriginal Canadians.” Journal of Applied Social

Psychology 40, no. 4 (2010): 899-916.

Write an argumentative and analytical research essay based on the story of Dr. Jekyll and Mr Hyde that takes a critical approach (i.e. Gender; Biographical; Historical; Psychological; etc.).

Description

Write an argumentative and analytical research essay based on the story of Dr. Jekyll and Mr Hyde that takes a critical approach (i.e. Gender; Biographical; Historical; Psychological; etc.). Must include quotes and references to the book along with 2-3 additional research sources.

Choose a leader who has been deeply involved in a change project and who will agree to be interviewed. Interview that leader and write an integration of what you have learned.

Description

Choose a leader who has been deeply involved in a change project and who will agree to be interviewed. Interview that leader and write an integration of what you have learned. The interview integration should contain the following components: 1- a description of the change, the success or failure of the project and the leaders role in it. And an explanation why you choose this leader in particular. 2- a summary of what the leader said about organisational change and what leads to effectiveness and success. 3- an evaluation of what the leader said including a comparison of the advice given by the leader and what you learned in the models from the sessions. 4- a section outlining the management implications of the leader’s messages.meaning the lessons learned and worthwhile to be shared. 2000-3350 words using APA formatting. I have added some notes in the add files.