Describe the mechanism of how digitalis (AKA Oubain) works at a molecular level to increase contractility (positive ionotrope)? Discuss the ion gradients, how they were created/maintained for a cell at resting membrane potential and the effects of this drug that lead to its action (rise in what ion and where) on muscle contraction.
Describe the mechanism of how digitalis (AKA Oubain) works at a molecular level to increase contractility (positive ionotrope)? Discuss the ion gradients, how they were created/maintained for a cell at resting membrane potential and the effects of this drug that lead to its action (rise in what ion and where) on muscle contraction.
